ea0056p581 | Obesity | ECE2018
Pivovarova Olga
, Gahwiler Roman
, Nikiforova Viktoria
, von Loffelholz Christian
, Lisec Jan
, Erban Alexander
, Zerkiebel Nic
, Willmitzer Lothar
, Pfeiffer Andreas F H
, Weickert Martin O
, Rudovich Natalia N
Introduction: Insulin resistance (IR), a pathological state of low sensitivity to insulin in humans and animlas, is closely associated with type 2 diabetes mellitus, obesity and cardiovasculare dieseas. IR can be quantified using detailed protocols, such as the euglycemic-hyperinsulinemic clamp (EC) technique and the intravenous glucose tolerance test, or based on indices derived from the oral glucose tolerance test. Although these indices showed greater association with the i...